CLINICAL EVIDENCE
Indications
Heartburn/GORD/NSAID induced erosions/ulcers
Heartburn is caused by stomach acid pushing up into the oesophagus, causing irritation and leading to a burning sensation in the chest. Absorbatox® is able to reduce the symptoms of heartburn as it binds some of the stimulants (histamine) and irritants responsible for acid hyper-secretion and thereby reduce the likelihood of discomfort.
ENGORD study
Absorbatox® significantly reduced the pain (56% reduction), discomfort (54% reduction), and number of heartburn episodes (44% reduction) in patients with GORD (p<0.05) (Figure 1-3). The Absorbatox® group also experienced more symptom free days ( 42%) compared to the placebo treated group.
NSAID
Non-steroidal anti-inflammatory medication
(NSAID) protection
NSAID induced gastritis study
Absorbatox® is thus associated with a prevention in gastritis (40%) and incidences of erosions (27%).
Reduction of heavy metals in plasma over 60 day clinical trial.
Bacterial toxin induced diarrhoea
Eating or drinking contaminated water may cause diarrhoea.The bacterial contained within the contaminated food and water produce toxins, which leads to the characteristic symptoms of diarrhoea. Absorbatox® has been shown to reduce the symptoms of diarrhoea, similarly to leading antidiarroeal drugs without being absorbed into the bloodstream. Symptoms of IBS (irritable bowel syndrome) IBS is a chronic disorder characterised by abdominal discomfort, bloating and altered defecation patterns. Absorbatox® aids in reducing the symptoms associated with IBS. Clinical evidence demonstrates a 40-50% reduction in symptoms compared to placebo.
Alcohol overindulgence (veisalgia)
A “hangover” is partially due to an increase in acid secretion and the release of inflammatory molecules by the stomach. Absorbatox® , reduces the symptoms of a “hangover” by binding these molecules in the GIT, preventing their actions on the surrounding tissues and on CNS when absorbed.